Endocrine Abstracts

Introduction: Diabetes mellitus (DM) is a chronic disease associated with multi-organ complications, including poor bone quality and high risk of frailty fracture. Bone and vascular complications seemed to be connected, as diabetic patients with atherosclerotic lesions show enhanced extrascheletric calcifications which in turn are associated with increased fracture risk. The aim of this study was to assessed bone mineral density (BMD) and trabecular bone score (TBS) in diabeti...

Male idiopathic osteoporosis is an underestimated disease, despite its clinical and social importance. The biochemical mechanisms are still poorly understood even if the interaction between genetic factors and hormone environment (especially gonadal steroids and GH) plays a undoubtful role. In previous studies we demonstrated low plasma total antioxidant capacity (TAC) in hypogonadal patients. The aim of this study was to investigate oxidative stress as risk factor for bone fr...